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Cyclic Octamer Peptoids: Simplified Isosters of Bioactive Fungal Cyclodepsipeptides

Cyclic peptoids have recently emerged as an important class of bioactive scaffolds with unique conformational properties and excellent metabolic stabilities. In this paper, we describe the design and synthesis of novel cyclic octamer peptoids as simplified isosters of mycotoxin depsipeptides bassian...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Assunta D’Amato, Giorgio Della Sala, Irene Izzo, Chiara Costabile, Yuichi Masuda, Francesco De Riccardis
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2018-07-01
Schriftenreihe:Molecules
Schlagworte:
cyclic peptoids
cyclodepsipeptides
insecticidal activity
conformational isomerism
structure-based design
peptidomimetics
Online-Zugang:http://www.mdpi.com/1420-3049/23/7/1779
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