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Sphingomyelin metabolism controls the shape and function of the Golgi cisternae

The flat Golgi cisterna is a highly conserved feature of eukaryotic cells, but how is this morphology achieved and is it related to its function in cargo sorting and export? A physical model of cisterna morphology led us to propose that sphingomyelin (SM) metabolism at the trans-Golgi membranes in m...

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Principais autores: Felix Campelo, Josse van Galen, Gabriele Turacchio, Seetharaman Parashuraman, Michael M Kozlov, María F García-Parajo, Vivek Malhotra
格式: Artigo
语言:Inglês
出版: eLife Sciences Publications Ltd 2017-05-01
丛编:eLife
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在线阅读:https://elifesciences.org/articles/24603
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