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Bergamottin Suppresses Metastasis of Lung Cancer Cells through Abrogation of Diverse Oncogenic Signaling Cascades and Epithelial-to-Mesenchymal Transition

Bergamottin (BGM) is a naturally occurring furanocoumarin and is known to inhibit the growth of tumor cells. However, there is no available evidence that BGM has an inhibitory effect on cancer metastasis, specifically on the epithelial-to-mesenchymal transition (EMT) process in the malignant cells....

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Principais autores: Jeong-Hyeon Ko, Dongwoo Nam, Jae-Young Um, Sang Hoon Jung, Gautam Sethi, Kwang Seok Ahn
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2018-07-01
Serier:Molecules
Fag:
bergamottin
EMT
metastasis
lung cancer
Online adgang:http://www.mdpi.com/1420-3049/23/7/1601
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