Colorectal carcinoma peritoneal metastases-derived organoids: results and perspective of a model for tailoring hyperthermic intraperitoneal chemotherapy from bench-to-bedside

Abstract Background Peritoneal metastases from colorectal cancer (CRCPM) are related to poor prognosis. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) have been reported to improve survival, but peritoneal recurrence rates are still high and there is no consensus o...

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Autori principali:	Luca Varinelli, Davide Battistessa, Marcello Guaglio, Susanna Zanutto, Oscar Illescas, Ewelina J. Lorenc, Federica Pisati, Shigeki Kusamura, Laura Cattaneo, Giovanna Sabella, Massimo Milione, Alessia Perbellini, Sara Noci, Cinzia Paolino, Elisabetta Kuhn, Margherita Galassi, Tommaso Cavalleri, Marcello Deraco, Manuela Gariboldi, Dario Baratti
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-05-01
Serie:	Journal of Experimental & Clinical Cancer Research
Soggetti:	Peritoneal metastases Colorectal cancer Organoids HIPEC Tailored therapies Chemotherapy
Accesso online:	https://doi.org/10.1186/s13046-024-03052-5
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