Integration host factor regulates antibiotic susceptibility through modulating alanine metabolism in Escherichia coli

PurposeThis study aimed to define how integration host factor (IHF) influences antibiotic susceptibility through metabolic regulation, using Escherichia coli ΔihfA and ΔihfB mutants.MethodsThe metabolic profiles of ΔihfA and ΔihfB mutants were analyzed by gas chromatography–mass spectrometry (GC–MS)...

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Váldodahkkit:	Huan-zhe Fu, Si-chen Yuan, Ming Jiang, Yu-Yan Chen, Xuan-xian Peng, Hui Li
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Frontiers Media S.A. 2026-02-01
Ráidu:	Frontiers in Microbiology
Fáttát:	alanine antibiotic susceptibility integration host factor metabolism reprogramming metabolomics
Liŋkkat:	https://www.frontiersin.org/articles/10.3389/fmicb.2025.1679242/full
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