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The microbial damage and host response framework: lesson learned from pathogenic survival trajectories and immunoinflammatory responses of Talaromyces marneffei infection

The adverse outcomes of fungal infection in mammalian hosts depend on the complex interactions between the host immune system and pathogen virulence-associated traits. The main clinical problems arise when the host response is either too weak to effectively eliminate the pathogen or overly aggressiv...

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Principais autores: Kritsada Pruksaphon, Artid Amsri, Juthatip Jeenkeawpieam, Patcharin Thammasit, Joshua D. Nosanchuk, Sirida Youngchim
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-08-01
coleção:Frontiers in Immunology
Assuntos:
Talaromyces marneffei
immunopathogenesis
damage-response framework (DRF)
latency
immune paradox
IRIS
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1448729/full
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