Collimator position optimization for proton minibeam radiation therapy

Abstract Proton minibeam radiation therapy (pMBRT) employs spatially fractionated dose distributions to reduce normal tissue toxicity. A key component is the multi-slit collimator (MSC), which shapes the beam into narrow, spatially separated minibeams. Small lateral shifts of the MSC relative to the...

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Главные авторы:	Nimita Shinde, Yuting Lin, Hao Gao
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Portfolio 2026-05-01
Серии:	Scientific Reports
Предметы:	Proton minibeam radiotherapy (pMBRT) Multi-slit collimator (MSC) Mixed integer programming (MIP)
Online-ссылка:	https://doi.org/10.1038/s41598-026-52573-w
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