Early in vitro results indicate that de-O-acetylated sialic acids increase Selectin binding in cancers
Cancers utilize a simple glycan, Sialic Acid, to engage in metastatic processes via the Sialic acid (Sia) -Selectin pathway. Selectins recognize and bind to sialylated substrates, resulting in adhesion, migration, and extravasation, however, how deviations from the canonical form of Sia regulate...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2024-12-01
|
| Schriftenreihe: | Frontiers in Oncology |
| Schlagworte: | |
| Online-Zugang: | https://www.frontiersin.org/articles/10.3389/fonc.2024.1443303/full |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|