Genetic knock-down of HDAC3 does not modify disease-related phenotypes in a mouse model of Huntington's disease.
Huntington's disease (HD) is an autosomal dominant progressive neurodegenerative disorder caused by an expansion of a CAG/polyglutamine repeat for which there are no disease modifying treatments. In recent years, transcriptional dysregulation has emerged as a pathogenic process that appears early in...
Na minha lista:
| Principais autores: | , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2012-01-01
|
| Serier: | PLoS ONE |
| Online adgang: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0031080&type=printable |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|