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Early epigenetic changes of Alzheimer’s disease in the human hippocampus

The discovery of new biomarkers would be very valuable to improve the detection of early Alzheimer’s disease (AD). DNA methylation marks may serve as epigenetic biomarkers of early AD. Here we identified epigenetic marks that are present in the human hippocampus from the earliest stages of AD. A pre...

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Principais autores: Idoia Blanco-Luquin, Blanca Acha, Amaya Urdánoz-Casado, Javier Sánchez-Ruiz De Gordoa, Janire Vicuña-Urriza, Miren Roldán, Alberto Labarga, María Victoria Zelaya, Carolina Cabello, Iván Méndez-López, Maite Mendioroz
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2020-10-01
Serier:Epigenetics
Fag:
early alzheimer’s disease
hippocampus
epigenetics
biomarkers
dna methylation
elovl2
git1
histone
fatty acid
Online adgang:http://dx.doi.org/10.1080/15592294.2020.1748917
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