Mimicking p14ARF phosphorylation influences its ability to restrain cell proliferation.

The INK4a/ARF locus on the short arm of chromosome 9 is one of the most frequently altered loci in human cancer. It is generally accepted that ARF is involved in oncogenic checkpoint pathways by sensitizing incipient cancer cells to undergo growth arrest or apoptosis through both p53-dependent and i...

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Hauptverfasser:	Maria Vivo, Michela Ranieri, Federica Sansone, Cristina Santoriello, Raffaele A Calogero, Viola Calabrò, Alessandra Pollice, Girolama La Mantia
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2013-01-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23308265/pdf/?tool=EBI
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