Metavert synergises with standard cytotoxics in human PDAC organoids and is associated with transcriptomic signatures of therapeutic response

Background: Despite some recent advances, pancreatic ductal adenocarcinoma (PDAC) remains a growing oncological challenge. New drugs capable of targeting more than one oncogenic pathway may be one way to improve patient outcomes. This study characterizes the effectiveness of Metavert a first-in-clas...

全面介紹

書目詳細資料

Principais autores:	Jingyu An, Roma Kurilov, Teresa Peccerella, Frank Bergmann, Mouad Edderkaoui, Adrian Lim, Xu Zhou, Katrin Pfütze, Angela Schulz, Stephan Wolf, Kai Hu, Christoph Springfeld, Sadaf S. Mughal, Lenart Zezlina, Franco Fortunato, Georg Beyer, Julia Mayerle, Susanne Roth, Johannes Hulkkonen, Daniela Merz, Shigenori Ei, Arianeb Mehrabi, Martin Loos, Mohammed Al-Saeedi, Christoph W. Michalski, Markus W. Büchler, Thilo Hackert, Benedikt Brors, Stephen J. Pandol, Peter Bailey, John P. Neoptolemos
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2024-11-01
叢編:	Translational Oncology
主題:	Pancreatic cancer Apoptosis Autophagy Molecular subtypes GSK3-β Histone deacetylases
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S1936523324002365
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!