Diet-responsive transcriptional regulation of insulin in a single neuron controls systemic metabolism.
Metabolic homeostasis is coordinated through a robust network of signaling pathways acting across all tissues. A key part of this network is insulin-like signaling, which is fundamental for surviving glucose stress. Here, we show that Caenorhabditis elegans fed excess dietary glucose reduce insulin-...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2022-05-01
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| Serier: | PLoS Biology |
| Online adgang: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3001655&type=printable |
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