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Enhanced Rishirilide Biosynthesis by a Rare In-Cluster Phosphopantetheinyl Transferase in Streptomyces xanthophaeus

ABSTRACT Phosphopantetheinyl transferases (PPTases) play important roles in activating apo-acyl carrier proteins (apo-ACPs) and apo-peptidyl carrier proteins (apo-PCPs) in both primary and secondary metabolism. PPTases catalyze the posttranslational modifications of those carrier proteins by covalen...

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Principais autores: Songya Zhang, Shuai Fan, Jing Zhu, Liying Zhou, Xiaohui Yan, Zhaoyong Yang, Tong Si, Tao Liu
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2022-12-01
סדרה:Microbiology Spectrum
נושאים:
rishirilide
Streptomyces
phosphopantetheinyl transferases
biosynthesis
גישה מקוונת:https://journals.asm.org/doi/10.1128/spectrum.03247-22
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