The Secreted Virulence Factor NADase of Group A Streptococcus Inhibits P2X7 Receptor-Mediated Release of IL-1β

The common human pathogen Group A Streptococcus (GAS) causes superficial as well as invasive, life-threatening diseases. An increase in the occurrence of invasive GAS infection by strains of the M1 and M89 serotypes has been correlated with increased expression of the genetically and functionally li...

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Detalhes bibliográficos

Principais autores:	Elsa Westerlund, Christine Valfridsson, Daisy X. Yi, Jenny J. Persson
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-06-01
coleção:	Frontiers in Immunology
Assuntos:	Group A Streptococcus NADase P2X7 IL-1β membrane permeabilization
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fimmu.2019.01385/full
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