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The Vascular Microenvironment in Glioblastoma: A Comprehensive Review

Glioblastoma multiforme, the deadliest primary brain tumor, is characterized by an excessive and aberrant neovascularization. The initial expectations raised by anti-angiogenic drugs were soon tempered due to their limited efficacy in improving the overall survival. Intrinsic resistance and escape m...

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Principais autores: Alejandra Mosteiro, Leire Pedrosa, Abel Ferrés, Diouldé Diao, Àngels Sierra, José Juan González
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-05-01
Serier:Biomedicines
Fag:
glioblastoma
tumor microenvironment
perivascular niche
angiogenesis
neovascularization
organoids
Online adgang:https://www.mdpi.com/2227-9059/10/6/1285
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