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Accounting for heterogeneity due to environmental sources in meta-analysis of genome-wide association studies

Abstract Meta-analysis of genome-wide association studies (GWAS) across diverse populations offers power gains to identify loci associated with complex traits and diseases. Often heterogeneity in effect sizes across populations will be correlated with genetic ancestry and environmental exposures (e....

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Siru Wang, Oyesola O. Ojewunmi, Abram Kamiza, Michele Ramsay, Andrew P. Morris, Tinashe Chikowore, Segun Fatumo, Jennifer L. Asimit
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2024-11-01
Rangatū:Communications Biology
Urunga tuihono:https://doi.org/10.1038/s42003-024-07236-9
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