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Pan‐cancer multi‐omics reveals DCAF7 as an immune‐modulating prognostic driver and Wnt/β‐catenin activator in hepatocellular carcinoma

Abstract Background DDB1 and CUL4‐associated factor 7 (DCAF7) is a WD‐repeat adaptor that recruits substrates to the CUL4DDB1 ubiquitinligase complex, but its pan‐cancer relevance and mechanistic contribution to tumor progression remain unclear. Methods Multi‐omics datasets (genomic, transcriptomic,...

Ful tanımlama

Kaydedildi:
Asıl Yazarlar: Ruina Luan, Hanbin Lin, Xin Zhao, Jianpeng Li, Maohe Chen, Shiping Luo, Xinjian Lin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wiley 2026-01-01
Seri Bilgileri:Clinical and Translational Medicine
Konular:
DCAF7
hepatocellular carcinoma
immune infiltration
pan‐cancer
Wnt signalling
Online Erişim:https://doi.org/10.1002/ctm2.70572
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