Footprint of positive selection in Treponema pallidum subsp. pallidum genome sequences suggests adaptive microevolution of the syphilis pathogen.

In the rabbit model of syphilis, infection phenotypes associated with the Nichols and Chicago strains of Treponema pallidum (T. pallidum), though similar, are not identical. Between these strains, significant differences are found in expression of, and antibody responses to some candidate virulence...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Lorenzo Giacani, Sujay Chattopadhyay, Arturo Centurion-Lara, Brendan M Jeffrey, Hoavan T Le, Barbara J Molini, Sheila A Lukehart, Evgeni V Sokurenko, Daniel D Rockey
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:	PLoS Neglected Tropical Diseases
Online-Zugang:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22720110/pdf/?tool=EBI
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!