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Patient-derived organoids (PDOs) as a novel in vitro model for neuroblastoma tumours

Abstract Background Neuroblastoma (NB) is a paediatric tumour of the sympathetic nervous system. Half of all cases are defined high-risk with an overall survival less than 40% at 5 years from diagnosis. The lack of in vitro models able to recapitulate the intrinsic heterogeneity of primary NB tumour...

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Main Authors: P. Fusco, B. Parisatto, E. Rampazzo, L. Persano, C. Frasson, A. Di Meglio, A. Leslz, L. Santoro, B. Cafferata, A. Zin, E. Cimetta, G. Basso, M. R. Esposito, G. P. Tonini
Format: Artigo
Language:Inglês
Published: BMC 2019-10-01
Series:BMC Cancer
Subjects:
Neuroblastoma
Patient-derived organoids
Preclinical model
Online Access:http://link.springer.com/article/10.1186/s12885-019-6149-4
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