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Adverse effects following anti-COVID-19 vaccination with mRNA-based BNT162b2 are alleviated by altering the route of administration and correlate with baseline enrichment of T and NK cell genes.

Ensuring high vaccination and even booster vaccination coverage is critical in preventing severe Coronavirus Disease 2019 (COVID-19). Among the various COVID-19 vaccines currently in use, the mRNA vaccines have shown remarkable effectiveness. However, systemic adverse events (AEs), such as postvacci...

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Principais autores: Ayesa Syenina, Esther S Gan, Justin Z N Toh, Ruklanthi de Alwis, Lowell Z Lin, Christine Y L Tham, Jia Xin Yee, Yan Shan Leong, Huizhen Sam, Charlene Cheong, Yii Ean Teh, Ian L E Wee, Dorothy H L Ng, Kuan Rong Chan, Jean X Y Sim, Shirin Kalimuddin, Eugenia Z Ong, Jenny G Low, Eng Eong Ooi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2022-05-01
coleção:PLoS Biology
Acesso em linha:https://doi.org/10.1371/journal.pbio.3001643
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