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Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells.

MIcrophthalmia-associated Transcription Factor (MITF) regulates melanocyte and melanoma physiology. We show that MITF associates the NURF chromatin-remodelling factor in melanoma cells. ShRNA-mediated silencing of the NURF subunit BPTF revealed its essential role in several melanoma cell lines and i...

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Autores principales: Dana Koludrovic, Patrick Laurette, Thomas Strub, Céline Keime, Madeleine Le Coz, Sebastien Coassolo, Gabrielle Mengus, Lionel Larue, Irwin Davidson
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2015-10-01
Colección:PLoS Genetics
Acceso en línea:https://doi.org/10.1371/journal.pgen.1005555
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