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Reactive Oxygen Species as Key Molecules in the Pathogenesis of Alcoholic Fatty Liver Disease and Nonalcoholic Fatty Liver Disease: Future Perspectives

Reactive oxygen species (ROS) are central to the progression of alcoholic fatty liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD). In ALD, ROS arise from alcohol metabolism (CYP2E1 and ADH/ALDH2), causing oxidative damage and fibrosis. In NAFLD, mitochondrial dysfunction, ER stress, a...

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Autors principals: Zhiqing Zhang, Hong Yang, Fei Han, Peng Guo
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2025-06-01
Col·lecció:Current Issues in Molecular Biology
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Accés en línia:https://www.mdpi.com/1467-3045/47/6/464
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