The IL‐21‐TET2‐AIM2‐c‐MAF pathway drives the T follicular helper cell response in lupus‐like disease

Abstract Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that involves T follicular helper (TFH) cell‐mediated humoral immune responses. Absent in melanoma 2 (human AIM2 and murine Aim2) is a well‐known component of the inflammasome in the innate immune system. Surprisingly, we ob...

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Detalhes bibliográficos

Principais autores:	Haijing Wu, Yaxiong Deng, Di Long, Ming Yang, Qianwen Li, Yu Feng, Yongjian Chen, Hong Qiu, Xin Huang, Zhenghao He, Longyuan Hu, Heng Yin, Guangdi Li, Yunkai Guo, Wenhan Du, Ming Zhao, Liwei Lu, Qianjin Lu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2022-03-01
coleção:	Clinical and Translational Medicine
Assuntos:	AIM2 systemic lupus erythematosus (SLE) T follicular helper cells (TFH)
Acesso em linha:	https://doi.org/10.1002/ctm2.781
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