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Understanding of the different roles of Noggin in the Noggin-BMP-2 and Noggin-BMP-9 dimer complexes at the molecular level

Abstract Bone morphogenetic proteins (BMPs) play crucial roles in tissue development and repair as growth factors. However, the clinical application of some type of BMPs is restricted due to their undefined and uncontrolled complex signaling pathways. This study investigates the interactions of BMPs...

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Autori principali: Suhyun Park, Dong Woo Lee, Min-Ho Park, Jue Yeon Lee, Dakshinamurthy Sivakumar, Sathishkumar Mudedla, Yeon Gyo Seo, Sangwook Wu, Yoon Jeong Park, Chong Pyung Chung
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2026-01-01
Serie:Scientific Reports
Accesso online:https://doi.org/10.1038/s41598-025-33735-8
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