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TRPV4 is the temperature-sensitive ion channel of human sperm

Ion channels control the ability of human sperm to fertilize the egg by triggering hyperactivated motility, which is regulated by membrane potential, intracellular pH, and cytosolic calcium. Previous studies unraveled three essential ion channels that regulate these parameters: (1) the Ca2+ channel...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Nadine Mundt, Marc Spehr, Polina V Lishko
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2018-07-01
Schriftenreihe:eLife
Schlagworte:
Online-Zugang:https://elifesciences.org/articles/35853
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