Single-nucleus RNA sequencing and deep tissue proteomics reveal distinct tumour microenvironment in stage-I and II cervical cancer

Abstract Background Cervical cancer (CC) is the 3rd most common cancer in women and the 4th leading cause of deaths in gynaecological malignancies, yet the exact progression of CC is inconclusive, mainly due to the high complexity of the changing tumour microenvironment (TME) at different stages of...

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Hlavní autoři:	Xiaosong Liu, Guoying Ni, Pingping Zhang, Hejie Li, Junjie Li, Bernardo Cavallazzi Sebold, Xiaolian Wu, Guoqiang Chen, Songhua Yuan, Tianfang Wang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2023-01-01
Edice:	Journal of Experimental & Clinical Cancer Research
Témata:	Single-nucleus RNA sequencing Quantitative proteomics Tumour microenvironment Cervical cancer Macrophage Collagen
On-line přístup:	https://doi.org/10.1186/s13046-023-02598-0
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