Oncolytic virotherapy reverses the immunosuppressive tumor microenvironment and its potential in combination with immunotherapy

Abstract It has been intensively reported that the immunosuppressive tumor microenvironment (TME) results in tumor resistance to immunotherapy, especially immune checkpoint blockade and chimeric T cell antigen therapy. As an emerging therapeutic agent, oncolytic viruses (OVs) can specifically kill m...

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Autors principals:	Yalei Zhang, Ye Li, Kun Chen, Ling Qian, Peng Wang
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2021-05-01
Col·lecció:	Cancer Cell International
Matèries:	Tumor microenvironment Oncolytic virus Immunotherapy Combination therapy
Accés en línia:	https://doi.org/10.1186/s12935-021-01972-2
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