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Return of polygenic risk scores in research: Stakeholders’ views on the eMERGE-IV study

Summary: Research on polygenic risk scores (PRSs) for common, genetically complex chronic diseases aims to improve health-related predictions, tailor risk-reducing interventions, and improve health outcomes. Yet, the study and use of PRSs in clinical settings raise equity, clinical, and regulatory c...

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Principais autores: Maya Sabatello, Suzanne Bakken, Wendy K. Chung, Elizabeth Cohn, Katherine D. Crew, Krzysztof Kiryluk, Rita Kukafka, Chunhua Weng, Paul S. Appelbaum
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-04-01
Serier:HGG Advances
Fag:
equity
polygenic risk scores, PRS
chronic diseases
return of results
barriers
translational genomic efforts
Online adgang:http://www.sciencedirect.com/science/article/pii/S2666247724000204
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