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Humanized c-Myc mouse.

BACKGROUND: A given tumor is usually dependent on the oncogene that is activated in the respective tumor entity. This phenomenon called oncogene addiction provides the rationale for attempts to target oncogene products in a therapeutic manner, be it by small molecules, by small interfering RNAs (siR...

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Autors principals: Frank M Lehmann, Samantha Feicht, Florian Helm, Anna Maurberger, Camilla Ladinig, Ursula Zimber-Strobl, Ralf Kühn, Josef Mautner, Armin Gerbitz, Georg W Bornkamm
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2012-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3409231?pdf=render
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