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CD73 and PD-L1 dual blockade amplifies antitumor efficacy of SBRT in murine PDAC models

Background Stereotactic body radiotherapy (SBRT) induces immunogenic cell death, leading to subsequent antitumor immune response that is in part counterbalanced by activation of immune evasive processes, for example, upregulation of programmed cell death-ligand 1 (PD-L1) and adenosine generating enz...

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Detalhes bibliográficos
Principais autores: Jian Ye, Brian A Belt, David C Linehan, Tara G Vrooman, Carl J Johnston, Edith M Lord, Scott A Gerber, Nicholas W Gavras, David C Keeley, Angela L Hughson, Gary Hannon, Maggie L Lesch, Jim Eyles
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2023-05-01
Colecção:Journal for ImmunoTherapy of Cancer
Acesso em linha:https://jitc.bmj.com/content/11/5/e006842.full
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