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Glutathione as a taste modulator: molecular mechanisms of interaction with umami and sweet taste receptors

Reduced L-glutathione (GSH) is a kokumi active tripeptide that enhances umami, salty, and sweet taste perceptions, probably via the calcium-sensing receptor (CaSR). In this study, we report that GSH is a partial agonist of the umami taste receptor (hTAS1R1/rTAS1R3). Using cellular assays, we reveale...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Clémence Cornut, Adeline Karolkowski, Maxence Lalis, Antoine Thomas, Rudy Menin, Jérémie Topin, Loïc Briand, Christine Belloir
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2025-12-01
Schriftenreihe:Food Chemistry: Molecular Sciences
Schlagworte:
Kokumi
G protein-coupled receptor
Ribonucleotide
TAS1R1/TAS1R3
Taste receptor
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2666566225000802
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