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Endothelin-1 and Vasomotor Tone Following Cardioplegic Ischemia/Reperfusion and Cardiopulmonary Bypass

Endothelin-1 is a potent regulator of vasomotor tone and promotes endothelium-dependent vasoconstriction of vascular smooth muscle. Dysregulated vasomotor tone is a hallmark of microvascular pathology following cardiac surgery involving cardioplegia and cardiopulmonary bypass (CPB). This review begi...

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Principais autores: Shawn Kant, Frank Sellke, Jun Feng
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-02-01
Serier:Cells
Fag:
endothelin-1
cardiopulmonary bypass
ischemia–reperfusion
vasomotor tone
microcirculation
microvascular dysfunction
Online adgang:https://www.mdpi.com/2073-4409/15/4/346
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