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Hyperforin, the major metabolite of St. John’s wort, exhibits pan-coronavirus antiviral activity

IntroductionThe COVID-19 pandemic caused by the SARS-CoV-2 virus has underscored the urgent necessity for the development of antiviral compounds that can effectively target coronaviruses. In this study, we present the first evidence of the antiviral efficacy of hyperforin, a major metabolite of St....

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Autori principali: Imelda Raczkiewicz, Céline Rivière, Peggy Bouquet, Lowiese Desmarets, Audrey Tarricone, Charline Camuzet, Nathan François, Gabriel Lefèvre, Fabiola Silva Angulo, Cyril Robil, François Trottein, Sevser Sahpaz, Jean Dubuisson, Sandrine Belouzard, Anne Goffard, Karin Séron
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2024-08-01
Serie:Frontiers in Microbiology
Soggetti:
coronaviruses
antiviral
natural compound
replication
broad-spectrum
Accesso online:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1443183/full
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