RNA-binding proteins distinguish between similar sequence motifs to promote targeted deadenylation by Ccr4-Not
The Ccr4-Not complex removes mRNA poly(A) tails to regulate eukaryotic mRNA stability and translation. RNA-binding proteins contribute to specificity by interacting with both Ccr4-Not and target mRNAs, but this is not fully understood. Here, we reconstitute accelerated and selective deadenylation of...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
eLife Sciences Publications Ltd
2019-01-01
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| Edice: | eLife |
| Témata: | |
| On-line přístup: | https://elifesciences.org/articles/40670 |
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