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Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub

Following infection of bacterial cells, bacteriophage modulate double-stranded DNA break repair pathways to protect themselves from host immunity systems and prioritise their own recombinases. Here, we present biochemical and structural analysis of two phage proteins, gp5.9 and Abc2, which target th...

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Bibliografiska uppgifter
Huvudupphov: Martin Wilkinson, Oliver J Wilkinson, Connie Feyerherm, Emma E Fletcher, Dale B Wigley, Mark S Dillingham
Materialtyp: Artigo
Språk:Inglês
Utgiven: eLife Sciences Publications Ltd 2022-12-01
Serie:eLife
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Länkar:https://elifesciences.org/articles/83409
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