QR-Code

Impact of renal impairment on the pharmacokinetic profile of intravenous difelikefalin, a kappa opioid receptor agonist for the treatment of pruritus

Abstract Background Difelikefalin is a selective kappa opioid receptor agonist that is approved for the treatment of moderate-to-severe pruritus associated with chronic kidney disease in adults undergoing hemodialysis (HD). In this study, we assessed the pharmacokinetics (PK) of intravenous (IV) dif...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Robert H. Spencer, Patrick K. Noonan, Thomas Marbury, Frédérique Menzaghi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2024-10-01
Schriftenreihe:BMC Nephrology
Schlagworte:
Difelikefalin
Kappa opioid receptor agonist
Pharmacokinetics
Tolerability
Chronic kidney disease
Pruritus
Online-Zugang:https://doi.org/10.1186/s12882-024-03790-w
Tags: Tag hinzufügen
Keine Tags, Fügen Sie das erste Tag hinzu!

Ähnliche Einträge