Mutation of the enterohemorrhagic Escherichia coli core LPS biosynthesis enzyme RfaD confers hypersusceptibility to host intestinal innate immunity in vivo

Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is an important foodborne pathogen causing severe diseases in humans worldwide. Currently, there is no specific treatment available for EHEC infection and the use of conventional antibiotics is contraindicated. Therefore, identification of potential...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Cheng-Ju Kuo, Jenn-Wei Chen, Hao-Chieh Chiu, Ching-Hao Teng, Tai-I Hsu, Pei-Jung Lu, Wan-Jr Syu, Sin-Tian Wang, Ting-Chen Chou, Chang-Shi Chen
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2016-08-01
Schriftenreihe:	Frontiers in Cellular and Infection Microbiology
Schlagworte:	Caenorhabditis elegans lipopolysaccharide (LPS) Antimicrobial peptides (AMPs) Enterohemorrhagic Escherichia coli (EHEC) Intestinal innate immunity RfaD/GmhD/WaaD
Online-Zugang:	http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00082/full
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