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CSF circulation and dispersion yield rapid clearance from intracranial compartments

In this paper, we used a computational model to estimate the clearance of a tracer driven by the circulation of cerebrospinal fluid (CSF) produced in the choroid plexus (CP) located within the lateral ventricles. CSF was assumed to exit the subarachnoid space (SAS) via different outflow routes such...

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Principais autores: Martin Hornkjøl, Lars Magnus Valnes, Geir Ringstad, Marie E. Rognes, Per-Kristian Eide, Kent-André Mardal, Vegard Vinje
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-09-01
Serier:Frontiers in Bioengineering and Biotechnology
Fag:
mathematical modelling
CSF dynamics
subarachnoid space
convection-diffusion
clearance
glymphatics
Online adgang:https://www.frontiersin.org/articles/10.3389/fbioe.2022.932469/full
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