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Conversion of epoxyeicosatrienoic acids (EETs) to chain-shortened epoxy fatty acids by human skin fibroblasts

Epoxyeicosatrienoic acids (EETs), the eicosanoid biomediators synthesized from arachidonic acid by cytochrome P450 epoxygenases, are inactivated in many tissues by conversion to dihydroxyeicosatrienoic acids (DHETs). However, we find that human skin fibroblasts convert EETs mostly to chain-shortened...

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Hlavní autoři: Xiang Fang, Terry L. Kaduce, Mike VanRollins, Neal L. Weintraub, Arthur A. Spector
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2000-01-01
Edice:Journal of Lipid Research
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S0022227520320757
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