Accounting for dependence induced by weighted KNN imputation in paired samples, motivated by a colorectal cancer study.

Missing data can arise in bioinformatics applications for a variety of reasons, and imputation methods are frequently applied to such data. We are motivated by a colorectal cancer study where miRNA expression was measured in paired tumor-normal samples of hundreds of patients, but data for many norm...

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Principais autores:	Anvar Suyundikov, John R Stevens, Christopher Corcoran, Jennifer Herrick, Roger K Wolff, Martha L Slattery
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2015-01-01
Serija:	PLoS ONE
Online dostop:	http://europepmc.org/articles/PMC4388652?pdf=render
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