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Chemotherapy-Induced Tumor Cell Death at the Crossroads Between Immunogenicity and Immunotolerance: Focus on Acute Myeloid Leukemia

In solid tumors and hematological malignancies, including acute myeloid leukemia, some chemotherapeutic agents, such as anthracyclines, have proven to activate an immune response via dendritic cell-based cross-priming of anti-tumor T lymphocytes. This process, known as immunogenic cell death, is cha...

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Principais autores: Darina Ocadlikova, Mariangela Lecciso, Alessandro Isidori, Federica Loscocco, Giuseppe Visani, Sergio Amadori, Michele Cavo, Antonio Curti
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019-10-01
Serier:Frontiers in Oncology
Fag:
acute myeloid leukemia
immunogenic cell death
dendritic cells
T regulatory cells
immunosuppression
Online adgang:https://www.frontiersin.org/article/10.3389/fonc.2019.01004/full
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