LKB1 suppression promotes cardiomyocyte regeneration via LKB1-AMPK-YAP axis

The regenerative potential of cardiomyocytes in adult mammals is limited. Previous studies reported that cardiomyocyte proliferation is suppressed by AMP-activated protein kinase (AMPK). The role of liver kinase B1 (LKB1), as the major upstream kinase for AMPK, on cardiomyocyte proliferation is unc...

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Principais autores:	Shuang Qu, Qiao Liao, Cheng Yu, Yue Chen, Han Luo, Xuewei Xia, Duofen He, Zaicheng Xu, Pedro A. Jose, Zhuxin Li, Wei Eric Wang, Qing Rex Lyu, Chunyu Zeng
格式:	Artigo
語言:	Inglês
出版:	Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2022-09-01
叢編:	Biomolecules & Biomedicine
主題:	LKB1 cardiomyocyte proliferation AMPK YAP
在線閱讀:	https://www.bjbms.org/ojs/index.php/bjbms/article/view/7225
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