Misfolding and aggregation in neurodegenerative diseases: protein quality control machinery as potential therapeutic clearance pathways
Abstract The primary challenge in today’s world of neuroscience is the search for new therapeutic possibilities for neurodegenerative disease. Central to these disorders lies among other factors, the aberrant folding, aggregation, and accumulation of proteins, resulting in the formation of toxic ent...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2024-08-01
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| Schriftenreihe: | Cell Communication and Signaling |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1186/s12964-024-01791-8 |
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