Antioxidant Compound, Oxyresveratrol, Inhibits APP Production through the AMPK/ULK1/mTOR-Mediated Autophagy Pathway in Mouse Cortical Astrocytes

Oxyresveratrol (OxyR), a well-known polyphenolic phytoalexin, possesses a wide range of pharmacological and biological properties, comprising antioxidant, anti-inflammatory, free radical scavenging, anti-cancer, and neuroprotective activities. Autophagy is a cellular self-degradation system that rem...

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Главные авторы:	Md. Ataur Rahman, Yoonjeong Cho, Ghilsoo Nam, Hyewhon Rhim
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2021-03-01
Серии:	Antioxidants
Предметы:	oxyresveratrol amyloid precursor protein (APP) AMPK-ULK1 mTOR LC3 puncta autophagy
Online-ссылка:	https://www.mdpi.com/2076-3921/10/3/408
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