GADD45α induction by nickel negatively regulates JNKs/p38 activation via promoting PP2Cα expression.

Growth arrest and DNA damage (GADD) 45α is a member of GADD inducible gene family, and is inducible in cell response to oxidative stress. GADD45α upregulation induces MKK4/JNK activation in some published experimental systems. However, we found here that the depletion of GADD45α (GADD45α-/-) in mous...

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Bibliographic Details

Main Authors:	Yonghui Yu, Jingxia Li, Yu Wan, Jianyi Lu, Jimin Gao, Chuanshu Huang
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0057185&type=printable
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