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The metabolic environment within solid tumors drives a complex crosstalk between macrophages and NK cells

The tumor microenvironment (TME) exerts significant metabolic limitations that influence the activity of invading immune cells. Among them, macrophages and natural killer (NK) cells are essential for coordinating anti-tumor immunity; however, the metabolic conditions of solid tumors have a significa...

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Principais autores: Didem Cakirsoy Akyoney, Joel Nordin, Samir El Andaloussi, Evren Alici
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-03-01
coleção:Frontiers in Immunology
Assuntos:
anti-tumor immunity
crosstalk
macrophage
metabolic competition
natural killer cells (NK cells)
solid tumor
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1726590/full
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