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Force measurements of TCR/pMHC recognition at T cell surface.

The rupture forces and adhesion frequencies of single recognition complexes between an affinity selected peptide/MHC complex and a TCR at a murine hybridoma surface were measured using Atomic Force Microscopy. When the CD8 coreceptor is absent, the adhesion frequency depends on the nature of the pep...

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Autors principals: Pierre-Henri Puech, Damien Nevoltris, Philippe Robert, Laurent Limozin, Claude Boyer, Pierre Bongrand
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2011-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3142151?pdf=render
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