Compartmentalized spatial profiling of the tumor microenvironment in head and neck squamous cell carcinoma identifies immune checkpoint molecules and tumor necrosis factor receptor superfamily members as biomarkers of response to immunotherapy

Mucosal head and neck squamous cell carcinoma (HNSCC) are the seventh most common cancer, with approximately 50% of patients living beyond 5 years. Immune checkpoint inhibitors (ICIs) have shown promising results in patients with recurrent or metastatic (R/M) disease, however, only a subset of patie...

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Autors principals:	Habib Sadeghirad, Ning Liu, James Monkman, Ning Ma, Bassem Ben Cheikh, Niyati Jhaveri, Chin Wee Tan, Majid Ebrahimi Warkiani, Mark N. Adams, Quan Nguyen, Rahul Ladwa, Oliver Braubach, Ken O’Byrne, Melissa Davis, Brett G. M. Hughes, Arutha Kulasinghe
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2023-04-01
Col·lecció:	Frontiers in Immunology
Matèries:	spatial proteomics head and neck cancer tumor microenvironment immunotherapy head and neck squamous cell carcinoma (HNSCC)
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1135489/full
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