Phased-assembly-driven pangenome graphs for structural variant genotyping and complex trait mapping in dairy cattle

Abstract Structural variants are an underexplored source of genetic diversity. As part of the FarmGTEx Project, here we report a Holstein breed-specific pangenome graph (H20D) using Minigraph-Cactus and 40 phased haploid assemblies from 20 cows. H20D outperforms both assembly- and read-based long-re...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Liu Yang, Yahui Gao, Kristen L. Kuhn, Nayan Bhowmik, Wenli Li, Geoffrey Zanton, Lingzhao Fang, John B. Cole, Congjun Li, Ransom L. Baldwin, VI, Curtis P. Van Tassell, Benjamin D. Rosen, Li Ma, Timothy P. L. Smith, George E. Liu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2026-01-01
Serie:	Nature Communications
Accesso online:	https://doi.org/10.1038/s41467-026-68807-4
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!